Cationic Antimicrobial Peptides Inactivate Shiga Toxin-Encoding Bacteriophages
نویسندگان
چکیده
منابع مشابه
Cationic Antimicrobial Peptides Inactivate Shiga Toxin-Encoding Bacteriophages
Shiga toxin (Stx) is the principal virulence factor during Shiga toxin-producing Escherichia coli (STEC) infections. We have previously reported the inactivation of bacteriophage encoding Stx after treatment with chitosan, a linear polysaccharide polymer with cationic properties. Cationic antimicrobial peptides (cAMPs) are short linear aminoacidic sequences, with a positive net charge, which di...
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In Shiga toxin-producing Escherichia coli (STEC), induction of Shiga toxin-encoding bacteriophages (Stx phages) causes the release of free phages that can later be found in the environment. The ability of Stx phages to survive different inactivation conditions determines their prevalence in the environment, the risk of stx transduction, and the generation of new STEC strains. We evaluated the i...
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To the Editor: In 2011, enteroaggregative Escherichia coli (EAEC) O104:H4 strains that produce Shiga toxins (EAEC-STEC) caused an outbreak of hemorrhagic disease affecting nearly 4,000 patients in Europe (1). During 2001–2013, several countries reported infections caused by EAEC O104:H4 and EAEC-STEC O104:H4 strains (1–9). Genomic analysis of EAEC and EAEC-STEC O104:H4 strains revealed high sim...
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ژورنال
عنوان ژورنال: Frontiers in Chemistry
سال: 2017
ISSN: 2296-2646
DOI: 10.3389/fchem.2017.00122